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  • aquinom85
    Research Bioinformaticist
    • Dec 2011
    • 19

    #1

    Breakdancer -o (single chromosome) segmentation fault

    Has anyone been able to figure out how to get breakdancer_max to run with the -o flag? Everywhere I've looked people have posted this same issue and I haven't seen any response to get it working and the devs don't respond to the issue, it's very frustrating.
  • aquinom85
    Research Bioinformaticist
    • Dec 2011
    • 19

    #2
    I think I might have figured it out, if you add the prefix chr to the number it seems to run without a segmentation fault. This seems like poor coding and even worse documentation.

    Comment

    • bwubb
      Member
      • Jan 2012
      • 61

      #3
      I have not gotten the -o flag to work at all. At first, it could not read my bam file index (because I did not have one). Once I solved that I tried running it with -o 17 or -o chr17.

      Neither produced a result. No errors, just made empty files. For the moment I am stumped.

      Comment

      • aquinom85
        Research Bioinformaticist
        • Dec 2011
        • 19

        #4
        I got -o to work in breakdancer-max1.2, apparently they fixed it there. However there are many unknown (UN) svs called and for some reason running each chr individually then running in -t mode is magnitudes of order faster than running the entire bam without -o or -t which is rather shocking.

        Comment

        • bwubb
          Member
          • Jan 2012
          • 61

          #5
          Interesting. Good to hear the issue is resolved.

          It appears I will not be able to get their latest version because of the methods they describe for installing it. Very frustrating. Maybe if I ask my computing admins very nicely they will do it for me...

          Comment

          • aquinom85
            Research Bioinformaticist
            • Dec 2011
            • 19

            #6
            Right, if you have your own Ubuntu machine or a vm it's easy but if your admins are anything like mine good luck because their github package is messed up and so source compiling doesn't work without a lot of work.

            Comment

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