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  • eoh001
    Member
    • Mar 2011
    • 19

    #1

    need mapping solutions for 454 reads

    Hello
    I tried to map 454 reads with GS reference mapper.
    I want to map them with different algorithm.
    Could you recommed any software good for 454 reads?
    Thanks!!!!
  • lukas1848
    Member
    • Jun 2011
    • 54

    #2
    You could try GMAP or bwa (with sw option set). Do you have PE or SE reads and do you have cDNA or genomic reads?

    Comment

    • ulz_peter
      Senior Member
      • Feb 2010
      • 219

      #3
      a very popular algorithm for 454 reads is SSAHA2

      Comment

      • KaiYe
        Senior Member
        • Jun 2009
        • 133

        #4
        a newer version of SSAHA2 is SMALT.

        Comment

        • adaptivegenome
          Super Moderator
          • Nov 2009
          • 436

          #5
          SMALT and BWA-SW are good. We have had some improved results by splitting the reads at homopolymers.

          Comment

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