GOSeq not finding database

[ETHANol]

I don't know what is going on here. GOSeq use to work fine for me. Now there seems to be some problem with finding the database. I think I've narrowed to problem down to the following code:

> library(goseq)
> GO.pvals=goseq(pwf,'hg19','ensGene')
Fetching GO annotations...
Error in library(paste(orgstring, "db", sep = "."), character.only = TRUE) : 
  there is no package called 'org.Hs.eg.db'

I'm running R version 2.13.2 and GOSeq version 1.4.0.

I have tried a few genome/gene ID combinations.

Any ideas would be greatly appreciated. Thanks.

[ETHANol]

Solved this one so I figured I would post the answer. I uninstalled R 2.14.2 and installed R 2.13.2 because the BSgenome package won't install in 2.14.2. It appears that goseq won't run in 2.13.2.

It's always nice when there are incompatibilities in the same work flow.

[ETHANol]

This issue has popped up again. I don't have any idea what is going on. Now it only happens when I am using the mm9 genome.

> library(goseq)
> GO.wall=goseq(pwf, "mm9", "geneSymbol")
Fetching GO annotations...
Error in library(paste(orgstring, "db", sep = "."), character.only = TRUE) : 
  there is no package called ‘org.Mm.eg.db’

It works when mm9 is replaced with hg19. Any ideas??

I am running R 2.14.2 and I can't seem to remember how to get the version of a R package but I believe it is the current version of goseq.

[yjzhang913]

hi, you shoud install the package you needed.

To install this package, start R and enter:

source("http://bioconductor.org/biocLite.R")
biocLite("org.Hs.eg.db")

[Nancy_Julia]

I tried to post a reply, but I think it disappeared. I too am having the same problem with that package, whether I use http or https. I need to work with mm9 for my assignment. I have installed the latest version of R and Rstudio. What more can I do?