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  • Mark
    replied
    A clustering tool like cd-hit should work.

    Leave a comment:


  • LizBent
    started a topic Comparing sets of contigs

    Comparing sets of contigs

    Hi, I have no reference genome for my organism, and I have de novo transcriptome contigs (made from 454 and Illumina data assembled with Newbler and Trinity, respectively, then combined with Cap3) for two different tissue types. I'd like to find out how many contigs are unique to each tissue type (that is, do not align at all with the contigs from the other tissue). Is there a tool out there that can do that?

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  • seqadmin
    Exploring the Dynamics of the Tumor Microenvironment
    by seqadmin




    The complexity of cancer is clearly demonstrated in the diverse ecosystem of the tumor microenvironment (TME). The TME is made up of numerous cell types and its development begins with the changes that happen during oncogenesis. “Genomic mutations, copy number changes, epigenetic alterations, and alternative gene expression occur to varying degrees within the affected tumor cells,” explained Andrea O’Hara, Ph.D., Strategic Technical Specialist at Azenta. “As...
    07-08-2024, 03:19 PM

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