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  • swan_r
    Junior Member
    • Apr 2012
    • 5

    #1

    Bowtie disadvantages

    Hey,
    Can anyone say me, what are disadvantages of Bowtie in bioinformatics?
  • westerman
    Rick Westerman
    • Jun 2008
    • 1104

    #2
    There are probably several. There is no one universal tool that does everything so every tool will have disadvantages. Your question is akin to asking "what are the disadvantages of using a screwdriver when building a house?" Anyway, with that rant out of the way, here is one disadvantage:

    Works on only short reads.

    Comment

    • swan_r
      Junior Member
      • Apr 2012
      • 5

      #3
      Thank you......Am not good at BWT .....Can you just teach me how to decode?..

      That is If BWT of a string is "erhte$", how can we know the original string?

      Comment

      • honey
        Senior Member
        • Feb 2010
        • 151

        #4
        Bowtie

        I think westerman is right. If you google differences between Bowtie vs BWA or SOAP2 etc etc you will find sevral posts on this forum as well as on other palteforms enlisting pros an dcons of each aligner. It will depend on what question one is asking?

        Comment

        • westerman
          Rick Westerman
          • Jun 2008
          • 1104

          #5
          @swan_r: You are changing the question. But that is fine. At least the topic is related. Here is a good link:



          Look at the animation and read some of his articles.

          Comment

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