Hi all,
I have used crest to find structure variations(SVs) in normal and cancer genome and it reported ~2500 SVs in normal genome and ~2600 SVs in cancer genome.
but when i ran crest to detect only somatic SVs, it reported only one SV.
Can any of you help me in getting more somatic SVs using crest?
Also some of the reported breakpoints have number of clipped reads equal to zero then why crest says that breakpoint at such position?
Any comment will be highly appreciated.....
I have used crest to find structure variations(SVs) in normal and cancer genome and it reported ~2500 SVs in normal genome and ~2600 SVs in cancer genome.
but when i ran crest to detect only somatic SVs, it reported only one SV.
Can any of you help me in getting more somatic SVs using crest?
Also some of the reported breakpoints have number of clipped reads equal to zero then why crest says that breakpoint at such position?
Any comment will be highly appreciated.....
