Hi,
What can be the cause of an increased number of 5-mers AAAAA and TTTTT?
Thank you.
What can be the cause of an increased number of 5-mers AAAAA and TTTTT?
Thank you.
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If you are sequencing repetitive regions of Human DNA for example, you would expect that. -
Could be Poly-A tails too, if this is RNA-seq, or if you just didn't RNase your samples that well. Transcriptome assemblies have more absurd poly-A coverage than that though.Comment
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Looks like polyA or lots of Alu sequences. What is the source of the data. This would help us debug.Comment
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