miRPara4.2 Released

weasteam

Member

Join Date: Dec 2008

Posts: 26
Share

Post
#1

miRPara4.2 Released

08-20-2012, 08:22 PM

miRPara4.2 is just released.

Updates:
fixed bug [uninitialized value $loop in lc at miRPara.pl line 813.]

optimized the UNAFold.pl & ct2out checking

multicore support (beta)

Home: http://www.whiov.ac.cn/bioinformatics/mirpara
Facebook: https://www.facebook.com/mirpara2009
Google Project: http://code.google.com/p/mirpara/

Further updates will be focus on:
Customer model training: we will release a script to train miRPara model based on customer sequences. e.g. human specific miRNAs can been used as input and trained a human specific model to predict known and novel human miRNAs.

Support for novel miRNA prediction from deep sequencing data: The miRPara will firstly add two 100-nt flanking sequences to both side of short sequence. Then predict the best secondary structure with lowest MFE and report miRNA candidates based on provided model.

Please feel free to let me know if you have any problem in installing or using miRPara. You can also leave a comment in our facebook or google project page.
Tags: None

Previous template Next

Beyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool

by SEQadmin2

CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.¹ But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).

Despite this, “CRISPR helped turn genome editing from a specialized technique into...
- Channel: Articles
07-31-2026, 11:01 AM
Proteomic Platforms: How to Choose the Right Analytical Strategy to Improve Detection and Clinical Applications

by SEQadmin2

Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.

The systematic characterization of the human proteome has...
- Channel: Articles
07-20-2026, 11:48 AM
Advanced Sequencing Platforms Tackle Neuroscience’s Toughest Genomics Problems

by SEQadmin2

Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
...
- Channel: Articles
07-09-2026, 11:10 AM

Topics	Statistics	Last Post
Consortium Completes First Full Diploid Human Genome by SEQadmin2 Started by SEQadmin2, Today, 07:41 AM	0 responses 9 views 0 reactions	Last Post by SEQadmin2 Today, 07:41 AM
Long-Read Sequencing Closes Decades-Old Gaps in the Medaka Genome by SEQadmin2 Started by SEQadmin2, 08-03-2026, 10:13 AM	0 responses 23 views 0 reactions	Last Post by SEQadmin2 08-03-2026, 10:13 AM
New Genomic Method Uncovers Ancient Hominin DNA by SEQadmin2 Started by SEQadmin2, 07-31-2026, 02:55 AM	0 responses 36 views 0 reactions	Last Post by SEQadmin2 07-31-2026, 02:55 AM
Study Captures the First Moments of DNA Replication by SEQadmin2 Started by SEQadmin2, 07-24-2026, 12:17 PM	0 responses 25 views 0 reactions	Last Post by SEQadmin2 07-24-2026, 12:17 PM

Unconfigured Ad

Latest Articles

ad_right_rmr

News