Hi everyone,
I would like to annouce a release of Tangram, a MEI (Mobile element insertion) detection toolbox based on MOSAIK alignment.
It is a stand-alone C/C++ command line program that is very fast and memory-efficient.
This version contains all the basic functions for MEI detection:
It takes MOSAIK aligned bam file(s) as input and output VCF files.
It is equipped with read-pair (sensitivity) and split-read (exact breakpoint) algorithms.
It can handle multiple bam files simultaneously (population dataset) to increase the sensitivity on the low-coverage dataset.
It also enables the MEI calling on a given chromsome region, say chr20:1-100000.
You can download it at: https://github.com/jiantao/Tangram
We are planning to add more SV types to this toolbox.
I would like to annouce a release of Tangram, a MEI (Mobile element insertion) detection toolbox based on MOSAIK alignment.
It is a stand-alone C/C++ command line program that is very fast and memory-efficient.
This version contains all the basic functions for MEI detection:
It takes MOSAIK aligned bam file(s) as input and output VCF files.
It is equipped with read-pair (sensitivity) and split-read (exact breakpoint) algorithms.
It can handle multiple bam files simultaneously (population dataset) to increase the sensitivity on the low-coverage dataset.
It also enables the MEI calling on a given chromsome region, say chr20:1-100000.
You can download it at: https://github.com/jiantao/Tangram
We are planning to add more SV types to this toolbox.
