Is there any software available at the moment for looking at data from illumina Omni arrays?
-
-
crlmm supposedly can also call genotypes for Omni arrays. However, I tried their 1.6.2 and found genotyping errors in the chrX SNPs. Not sure if it is fixed in their latest version though. -
Illumina Omni CNV analysis
Hi,
I have problem in analyzing CNV for one sample. In this sample LRR profile around(0.0) remains FLAT, though not BAF profile (0.6 & 0.4) and as per ASCAT (software I am using) there is no copy number change.
Has any of you come across a similar issue?
Was wondering if it possible to analyze data with low cellularity and is more a technical issue of the software I am using.
Any pointers would be very helpful.
Best
ShrutiComment
-
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM -
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...07-20-2026, 11:48 AM -
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
...07-09-2026, 11:10 AM
Comment