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  • revision
    Junior Member
    • Oct 2012
    • 4

    Sequence alignment question Help Please Urgent!

    Align the glucagon sequences for human (NM_002054.4) , cow (NM_173916.3) and chicken(Y07539.1). Nucleotide sequences
    Find the conserved region that includes SRRAQDFVQWLM. Immediately after this what is asparagine substituted for in the chicken?

    Options

    1) glutamate
    2) serine
    3) glycine
    4) proline
  • GW_OK
    Senior Member
    • Sep 2009
    • 411

    #2
    This sounds suspiciously like a homework question.

    Comment

    • ECO
      --Site Admin--
      • Oct 2007
      • 1360

      #3
      Urgent. Ha. The things people will do NOT to learn/understand material!

      Comment

      • mnkyboy
        Member
        • Mar 2009
        • 87

        #4
        The answer is D.

        Comment

        • HESmith
          Senior Member
          • Oct 2009
          • 512

          #5
          Originally posted by mnkyboy View Post
          The answer is D.
          aka aspartate. Clearly a trick question, since that's not one of the options.

          Comment

          • revision
            Junior Member
            • Oct 2012
            • 4

            #6
            So the answer is proline but after aligning the sequences and finding the conserved region how did you come to the conclusion that asparate is proline.
            Can you send me a link that explains this. Thank you.

            Comment

            • GW_OK
              Senior Member
              • Sep 2009
              • 411

              #7
              The single letter code for Aspartate is 'D'.


              Makes perfect sense to me.

              Comment

              • revision
                Junior Member
                • Oct 2012
                • 4

                #8
                How can the answer be aspartate if its not one of the options?

                Comment

                • HESmith
                  Senior Member
                  • Oct 2009
                  • 512

                  #9
                  Originally posted by revision View Post
                  How can the answer be aspartate if its not one of the options?
                  (sigh) You really don't understand?

                  mnkyboy said the answer was D (which is also not one of your options); D is the single-letter code for aspartate. It was a joke (indicated by ).

                  Comment

                  • BAMseek
                    Senior Member
                    • Apr 2011
                    • 124

                    #10
                    Tortoise: 'MU? What is this 'MU'? What about the dog? What about Buddha-nature? What's the answer?

                    Achilles: Oh, but 'MU' is Joshu's answer. By saying 'MU', Joshu let the other monk know that only by not asking such questions can one know the answer to them.

                    Tortoise: Joshu "unasked" the question.

                    Achilles: Exactly!

                    Tortoise: 'MU' sounds like a handy thing to have around. I'd like unask a question or two, sometimes. I guess I'm beginning to get the hang of Zen.
                    The answer is 'mu' (or D - Aspartate).

                    Comment

                    • swbarnes2
                      Senior Member
                      • May 2008
                      • 910

                      #11
                      Aww, you guys are teasing the teenager.

                      This is a site for grown-ups. People are amusing themselves at your expense. So go do your own homework.

                      Comment

                      • HESmith
                        Senior Member
                        • Oct 2009
                        • 512

                        #12
                        BAMseek, I'm sure you confused revision even more (but I appreciate the Hofstadter quote).

                        Comment

                        • BAMseek
                          Senior Member
                          • Apr 2011
                          • 124

                          #13
                          Originally posted by HESmith View Post
                          BAMseek, I'm sure you confused revision even more (but I appreciate the Hofstadter quote).
                          Yeah, that is probably true (and I'm glad someone knows what I am talking about).

                          revision -

                          I think you may get some more (serious) responses if you are upfront that it is a homework assignment, and you try to explain how far you have gotten with the problem. Then people may be able to nudge you in the right direction. People here are always willing to help, but I think only after they've seen you tried putting in the work yourself.

                          Justin

                          Comment

                          • revision
                            Junior Member
                            • Oct 2012
                            • 4

                            #14
                            Wow I'm completely speechless.

                            Comment

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