Unconfigured Ad

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts
  • nanto
    Member
    • Sep 2012
    • 19

    SAM HMM DNA alignment

    After coming long way through blastn, and all of it's big family, to all kinds of burrows-wheeler aligners, now I'm interested in using HMM for dna alignment. I would use HMMER, but sequences are from PacBio so it's not an option.

    Does anyone has any clue how to do it?

    Best for me would be advices like:

    which module use first (buildmodel I suppose)

    Build model on what, query sequence or reference?

    How to align (just basics, with no specification, I will deal with it).
  • huliang1000
    Junior Member
    • Jun 2013
    • 1

    #2
    Sam hmm

    hi
    have you got through about SAM HMM, can I ask you some question?
    my email: [email protected] ,waiting for your reply

    Comment

    Latest Articles

    Collapse

    • mylaser
      Reply to Advanced Sequencing Platforms Tackle Neuroscience’s Toughest Genomics Problems
      by mylaser
      Kheloyar – Everything You Need to Know About Kheloyaar Login and Kheoyar Id
      If you are looking for an online gaming platform that offers a user-friendly experience, Kheloyar has become a name that many users search for. Whether you're interested in creating a new account, accessing your dashboard through Kheloyaar Login, or learning how to obtain a Kheoyar Id, understanding the platform's features and account process is essential.
      This guide explains everything you need to know about...
      Yesterday, 01:13 AM
    • SEQadmin2
      Advanced Sequencing Platforms Tackle Neuroscience’s Toughest Genomics Problems
      by SEQadmin2



      Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
      ...
      07-09-2026, 11:10 AM
    • SEQadmin2
      Cancer Drug Resistance: The Lingering Barrier to Rising Survival
      by SEQadmin2



      Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.

      There is no single reason why many patients don’t respond to treatment as expected. Cancer is...
      07-08-2026, 05:17 AM

    ad_right_rmr

    Collapse

    News

    Collapse

    Topics Statistics Last Post
    Started by SEQadmin2, 07-09-2026, 10:04 AM
    0 responses
    17 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 07-08-2026, 10:08 AM
    0 responses
    10 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 07-07-2026, 11:05 AM
    0 responses
    25 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 07-02-2026, 11:08 AM
    0 responses
    31 views
    0 reactions
    Last Post SEQadmin2  
    Working...