I am trying to figure out what would be a good system for our ngs analysis needs - we are pretty new to working with the data, but it has become quite clear that we need a dedicated system for analysis.
We do not do sequencing ourselves, only analysis (mapping; resequencing, RNAseq, variant calling) on the data provided. We work exclusively with eucaryotic genomes. We want to use open source tools to begin with, but may want to explore commercial software at some stage, so the hardware should support this/be upgrade-able.
Outsourcing the analysis is often a problem - either due to confidentiality issues or lack of capacity in core facitlities, or simply when we figure out some interesting analyses for an old data set at a later date - which is why we like to analyse ourselves.
For now, we are definitely talking small scale - a few runs per year for various purposes, parallelisation not required, so I am thinking a separate dedicated work station.
Just what would be a reasonable setup?
How many cores? RAM? Internal memory/HD? Long term data storage will be on a network drive so less pressure on an internal HD, space wise.
If I could chose, I'd prefer OSX as an operating system to a Linux distribution.
Any thoughts, community?
Cheers,
TabeaK
