Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • Tjcooper
    Junior Member
    • Nov 2012
    • 1

    #1

    Correlation of CHiP-Seq with ENCODE transcription factor data

    Good afternoon

    I am currently an undergraduate student of molecular biology carrying out my final year dissertation project. The group I am working with have carried out a global ChIP-seq and microarray study centred on a specific non-DNA binding viral protein and I have been using chromosome conformation capture techniques to probe mechanisms by which this protein regulates target genes.

    As this protein does not bind DNA directly, as a small side project, I also want to identify potential candidates for targeting factors. A few are currently known but many are likely left to be found.

    I was wondering if there was a automated way to use the ENCODE transcription factor data to pull out a list of factors which associate at the same loci as this viral factor. I could do this manually via the UCSC genome browser but of course this would be very time consuming and I could not do it on a global level. I also understand this is a rather bias and simplistic approach but i'm only looking for a basic starting point to look for factors which may warrant further investigation.

    Many thanks for any help!

    -TJ

Latest Articles

Collapse

  • SEQadmin2
    Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
    by SEQadmin2



    Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

    Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating
    ...
    10-14-2026, 09:55 AM
  • SEQadmin2
    New Genomics Technologies Take Aim at Long-Standing Limits
    by SEQadmin2


    Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.

    We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing
    ...
    09-28-2026, 10:25 AM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by SEQadmin2, Yesterday, 11:13 AM
0 responses
17 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, Yesterday, 10:48 AM
0 responses
18 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-15-2026, 10:52 AM
0 responses
36 views
0 reactions
Last Post SEQadmin2  
Started by SEQadmin2, 10-14-2026, 05:39 AM
0 responses
42 views
0 reactions
Last Post SEQadmin2  
Working...