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  • carmeyeii
    Senior Member
    • Mar 2011
    • 137

    #1

    --best --strata in paired end alignments using Bowtie

    Does anyone know why the --best --strata options are not valid when working with paired-end reads?

    This is a very useful parameter, since the analysis of my data requires to allow multi-mappers, but only those with the top alignment score.

    Any input would be greatly appreciated!

    Carmen

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