I'm mapping reads (around 20 mil avg 92bp in length) using tophat 2.0.4 and 2.0.6. 2.0.4 maps to around 91% while 2.0.6 maps to only 67%. Does anyone know what accounts for such a huge difference?
Both tophats are run with default parameters and GTF files.
Bowtie version: 2.0.0.7
Samtools version: 0.1.18.0
Thanks!
Both tophats are run with default parameters and GTF files.
Bowtie version: 2.0.0.7
Samtools version: 0.1.18.0
Thanks!
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