Hi all,
Does anyone know of a good tool to calculate SNV transition/transversion profiles??
Meaning the proportion of C>A, T>C C in CpG mutations etc... givin a list of mutations?
The hardest part is getting the CpG contexts. It's relatively easy to code given a list of ref to alt bases, but it's much more complicated for me to annotate the neighbouring base!! I was wondering if there was a good tool for this.
Many thanks,
- Torch
Does anyone know of a good tool to calculate SNV transition/transversion profiles??
Meaning the proportion of C>A, T>C C in CpG mutations etc... givin a list of mutations?
The hardest part is getting the CpG contexts. It's relatively easy to code given a list of ref to alt bases, but it's much more complicated for me to annotate the neighbouring base!! I was wondering if there was a good tool for this.
Many thanks,
- Torch