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  • fadista
    Member
    • Sep 2008
    • 37
    #1

    correction for gene length in burden tests

    Hi,

    I would like to know if any of the gene rare variant burden tests out there tries to correct for gene length, or number of variants per gene.
    As far as I know (might be wrong) this doesn´t seem to be implemented in any test. This would lead to always favor significant results for longer genes vs. shorter genes.

    Best regards,
    João
    Tags: burden tests, gene length
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