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  • CGHa (CNV help)

    Hi Every body,

    I am new to bioinformatics ,basically from computer science back ground.
    I have worked with SNP in plants but now working with data in Cancer research.

    Its CGHa,affymatrix 6.0

    Its cancer patient array without control(normal cells)

    Here i will provide you some detail about my data.

    I got my CGHa data from GISTIC software from broad institute.
    Which contains two files

    1)Amplifications 2) Deletions.

    Fields in the amplification files are
    i)cytoband ii)q value iii)residual q value iv)wide peak boundaries v)genes in wide peak

    Wide peak boudaries contain list of genes contains in it.

    Same way i have file for deletions.

    Now i am looking for coding mutations and non-coding variants.
    How do i do that using bioinformatics.
    All help from biological understanding to bioinformatics tools is highly appreciated.

    Thank you all in advance.
    Plantdata

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