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  • Searching known TF binding sites for matching motif?

    Hi,

    I have a list of DMRs that I have sent through MEME to identify common motifs. I would like to search known transcription factor binding sites for these motifs to see whether any of them correspond. Is there a tool that can do this? This is for humans.

    Thanks!

  • #2
    You can try Homer, a tool for ChIP-Seq analysis, including Motif analysis, known motifs will be found.
    Engineer of Data Analysis
    E-mail: [email protected]

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    • #3
      what do you mean by "know transcription factor binding sites"?
      if you mean the binding sites determined by ChIP-seq experimentally, I think you have to download the corresponding ChIP-seq data for corresponding TFs, peak call to generate a bed file, and just do a overlap with your DMRs to see any of them overlap.

      you can do it through Galaxy or you can use bedtools.

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