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  • Problems with SVDetect cnv

    Sv Detect cnv asks for following things :


    1- Calculation of depth-of-coverage log-ratios

    >> SVDetect cnv -conf <configuration_file>

    a- Usage parameters in the <detection> block:

    -- split_mate_file (m)
    Flag to split the original mate file per chromosome for parallel computing
    -boolean, value= 1 (run), 0 (skip - already done)

    -- window_size(m)
    size of the sliding-window used for partioning the genome in bp
    -integer, ex: 30000

    -- step_length(m)
    length of the sliding-window step in bp, set this parameter to get overlapped windows
    -integer, ex: 10000

    --mates_file_ref(m)
    full path to the normal mate-pair input data file of the reference
    -text, ex: /align/bowtie/reference_norm_mates.sam



    I have problem with mates_file_ref. I put the full mapped sam file of the sample, it doesn't work. the Human reference Genome human_g1k_v37_Ensembl_MT_66.fasta doesn't work (it shouldn't work ideally).

    Does anyone has any idea which file path should I provide there.

    Thanks in advance

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