I am currently working with assembly programs and most of the assemblers output max contig length and N50. But many papers also report percent of reference genome covered by the contigs in their results. So if I have a set of contigs and a reference genome then how can I measure the percent of reference genome covered by the contigs of length greater than say x. I used NUCMER but I can get a delta or coords file as an output but not the exact percentage. Anyone knows of any tool which can output this parameter?
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM