I want to convert FASTA files to pgSNP. Ive googled high and low and cant find a way to do it. Is it even possible? Can i somehow do it with bioperl or biopython or bioruby?
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That's not a conversion, which is why google isn't giving you any results. A pgSNP format file is a text file describing variants in a genome. A fasta file is a (typically) nucleotide sequence. The sequence could be of a genome, a transcript, or even just a read (from high-throughput or even Sanger sequencing). Presumably, you need to call variants or find the differences between your fasta file(s) and the reference. If you provided more details regarding exactly what you have, someone can probably give you some hints on how to proceed. -
I have a couple of FASTA files containing sequences of different neanderthals. I want to compare the results of living people's 23andme results ( in pgSNP format ) to the neanderthal samples.Comment
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM
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