I'm trying to "follow along" with this paper as an exercise to teach myself a little bit about evolutionary rates. I'm having some trouble finding the "annotated gene predictions" on the IMG site and was hoping someone with more experience navigating the site could help me out. I (so far) have only been able to find the complete genome. Can someone help me overcome my admittedly naive problem with this as an example?
-
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM