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  • mozack
    Junior Member
    • Jun 2013
    • 8

    #1

    SAM spec / BWA-MEM

    Hello,

    The release notes for bwa-mem 0.7.5 reference an upcoming SAM spec v1.5. Does anyone know if a preview of the coming spec changes is available publicly?


    "Changed the way a chimeric alignment is reported (conforming to the upcoming
    SAM spec v1.5). With 0.7.5, if the read has a chimeric alignment, the paired
    or the top hit uses soft clipping and is marked with neither 0x800 nor 0x100
    bits. All the other hits part of the chimeric alignment will use hard
    clipping and be marked with 0x800 if option "-M" is not in use, or marked
    with 0x100 otherwise."


    Thanks!
  • BAMseek
    Senior Member
    • Apr 2011
    • 124

    #2
    I found the latex for it:

    Specifications of SAM/BAM and related high-throughput sequencing file formats - samtools/hts-specs


    Looks like you'll have to convert latex to pdf if you want to make it more readable.

    Justin

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