I was thinking of using OrthoMCL to cluster RNA sequences. Does anybody know whether it is OK? Thanks!
Unconfigured Ad
Collapse
X
-
Tags: None
-
As far as I know, orthoMCL uses a set of protein sequences as input. So orthoMCL will not work with RNA (cDNA) sequences directly (but would after translating them into protein sequences).
In any case, homology/orthology assessment is much more powerful for protein sequences than for DNA sequences.
-
Thanks so much!Originally posted by robinvvelzen View PostAs far as I know, orthoMCL uses a set of protein sequences as input. So orthoMCL will not work with RNA (cDNA) sequences directly (but would after translating them into protein sequences).
In any case, homology/orthology assessment is much more powerful for protein sequences than for DNA sequences.
Comment
Latest Articles
Collapse
-
by SEQadmin2
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...-
Channel: Articles
10-14-2026, 09:55 AM -
ad_right_rmr
Collapse
News
Collapse
| Topics | Statistics | Last Post | ||
|---|---|---|---|---|
|
Genome Sequencing Reveals Large, Repeat-Rich DNA in Trapdoor Spider Named for Stephen Colbert
by SEQadmin2
Started by SEQadmin2, Yesterday, 09:57 AM
|
0 responses
20 views
0 reactions
|
Last Post
by SEQadmin2
Yesterday, 09:57 AM
|
||
|
Started by SEQadmin2, Yesterday, 09:51 AM
|
0 responses
11 views
0 reactions
|
Last Post
by SEQadmin2
Yesterday, 09:51 AM
|
||
|
Started by SEQadmin2, 10-22-2026, 11:13 AM
|
0 responses
67 views
0 reactions
|
Last Post
by SEQadmin2
10-22-2026, 11:13 AM
|
||
|
Started by SEQadmin2, 10-22-2026, 10:48 AM
|
0 responses
47 views
0 reactions
|
Last Post
by SEQadmin2
10-22-2026, 10:48 AM
|
Comment