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  • cmccabe
    started a topic transition / travnsversion ratio

    transition / travnsversion ratio

    Hello,

    I am trying to figure out:

    17 transitions and 6 transversions = 2.83

    These numbers are from a panel of 14 genes, but what does this # mean? The sequence is aligned to the whole genome and the 14 genes are targeted. Thank you.

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  • seqadmin
    Exploring the Dynamics of the Tumor Microenvironment
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    The complexity of cancer is clearly demonstrated in the diverse ecosystem of the tumor microenvironment (TME). The TME is made up of numerous cell types and its development begins with the changes that happen during oncogenesis. “Genomic mutations, copy number changes, epigenetic alterations, and alternative gene expression occur to varying degrees within the affected tumor cells,” explained Andrea O’Hara, Ph.D., Strategic Technical Specialist at Azenta. “As...
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