I have whole bacterial genomes (very closely related) aligned and I would like to get the information of only the SNPs so that I can do some LD analysis. I would like to try to get them in the ped and map or plink formats preferably so that I can use them as imput for tassel. I haven't come across any tool that does this. The alignment is in nexus but I dont have a problem with any other msa format. Has any of you heard or had this issue?
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM -
Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing...