I have whole bacterial genomes (very closely related) aligned and I would like to get the information of only the SNPs so that I can do some LD analysis. I would like to try to get them in the ped and map or plink formats preferably so that I can use them as imput for tassel. I haven't come across any tool that does this. The alignment is in nexus but I dont have a problem with any other msa format. Has any of you heard or had this issue?
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM