Illumina Alignment
Has anyone used Softgenetics NEXTGENe or CLC genomics workbench? I am trying to find a analysis package that will help with gap analysis. After a run on the Illumina Genome Analyzer it will align the reference sequence to my sample run, but Illumina will not give me a spreadsheet print out of the gaps between the reference and the sample run. Has anyone used the above software for this? Are there other suggestions for this issue?
-
-
SoftGenetics NextGENe provides the solution to the problem. It allows us to check the alignment results of reference sequence to sample run in both graphical view and spreadsheet view. User can easily print and save these results as well. -
Full disclosure: akhil is from a company that resells NextGENe.Originally posted by akhil View PostComment
-
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM
Comment