Competing endogenous RNAs(ceRNAs) hypothesis: ceRNAs regulate other RNA transcripts (e.g., PTEN) by competing for shared microRNAs. They are playing important roles in pathological conditions, such as cancer. (Salmena et al. 2011 Cell)
We identified ~200,000 (P<0.05) and ~10,000 (FDR<0.05) ceRNA pairs from CLIP-supported miRNA target sites . We developed ceRNAFunction tool to predict the functions of lncRNAs and protein-coding genes from ceRNA regulatory networks.
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We identified ~200,000 (P<0.05) and ~10,000 (FDR<0.05) ceRNA pairs from CLIP-supported miRNA target sites . We developed ceRNAFunction tool to predict the functions of lncRNAs and protein-coding genes from ceRNA regulatory networks.
We are looking forward to hearing your feedback and hope you enjoy it.
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