Dear all,
I want to learn the data analysis of Illumina methylation 450K chip, I found there are several files on the GEO database, like SOFT, TXT, GSE....tar, I didn't fully understand the description of them, so I hope some could help me explaining them simply. for example, which file is the output of Illumina GenomeStudio software, hmm ... the matrix file should the methylation level of each CpG site of every sample, however, I don't know how the value has been normalized.
thank you all very much.
xiao
I want to learn the data analysis of Illumina methylation 450K chip, I found there are several files on the GEO database, like SOFT, TXT, GSE....tar, I didn't fully understand the description of them, so I hope some could help me explaining them simply. for example, which file is the output of Illumina GenomeStudio software, hmm ... the matrix file should the methylation level of each CpG site of every sample, however, I don't know how the value has been normalized.
thank you all very much.
xiao