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  • medalofhonour
    Member
    • Jul 2011
    • 18

    #1

    GATK error "Annotations with zero variance"

    Hi,

    I am wondering if anyone has ever come across this GATK error during the VariantRecalibrator step
    Last edited by medalofhonour; 10-09-2013, 10:26 AM.
  • Elsie
    Member
    • Mar 2011
    • 85

    #2
    Yes, I've seen it. The error message says "Please do NOT post this error to the GATK forum unless you have really tried to fix it yourself." so I had assumed that it was my mistake, something wrong with the command line. I reran VariantRecalibration with only the minimum of annotations, e.g. -an BaseQRankSum -an FS, and the error went away, so I assume it is when you are trying to use an annotation which only has minimal representation/information in the training variants in the input callset.

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