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  • pythonscript to find the number of homologous genegroups within a genome.

    Dear all, please kindly help me to
    solve this problem by python script
    writing. I am a beginner in script
    writing.
    Problem: A homologous gene group
    consists of genes, which have an
    alignment to at least one other gene
    in the group with both a % sequence
    coverage and % identity equal to or higher than a
    given stringency cutoff. Write a python program
    to find the number of homologous gene groups
    within a genome at various levels of stringency.
    For example with a stringency of 10, every gene
    in a group should have a % sequence coverage
    and % identity of at least 10% with at least one
    other gene in the group. The program should take
    a single genome file in genbank format on the
    command line and write a csv file called
    "output.csv" in the directory. The ouput file
    should consist of 10 lines, each line should have
    the stringency used (0 to 100, in increments of
    10) and the number of homology groups. (See
    example below). write the python program as a
    txt file.
    Example: 0,13456 10,234 20,234 30,200 40,190
    50,187 60,187 70,100 80,95 90,55 100,45

  • #2
    That's quite hardcore homework you have there, especially if you're supposed to do it from scratch
    savetherhino.org

    Comment


    • #3
      yes its a hardcore one but have to solve it. I need all of your help. As I am a beginner in programing language from a biological background have no idea what to do. something good is depend on it. please kindly help me.

      Comment


      • #4
        Originally posted by Arif Mahmud View Post
        yes its a hardcore one but have to solve it. I need all of your help. As I am a beginner in programing language from a biological background have no idea what to do. something good is depend on it. please kindly help me.
        Drop out and take a class that is more to your level? Beginners should be doing hello worlds and such. Not this. Are you allowed to use other programs in your script or are you supposed to implement multiple sequence alignment etc. from scratch?
        savetherhino.org

        Comment


        • #5
          its a requirement. if I solved this problem my application process will be further proceed. only python script will be allowed. yes I think about implementation of multiple sequence alignment

          Comment


          • #6
            Well, I wouldn't know how to implement such things from scratch. It seems to me like you're applying to the wrong place. I wouldn't apply to say some physics grad school with my high school physics only background. Anyway, good luck. I doubt anyone here will help you 'cheat' your way through this, but who knows..
            savetherhino.org

            Comment

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