Calling de novo mutations

[tracecakes]

Hi all,

Is anybody familiar with calling de novo mutations from whole genome sequences of parent-offspring trios (computationally) ? I have read that samtools and VarScan can do this but I would like to hear everyones experiences.

Cheers!

[Mr.Zurich1992]

Hi all,

Is anybody familiar with calling de novo mutations from whole genome sequences of parent-offspring trios (computationally) ? I have read that samtools and VarScan can do this but I would like to hear everyones experiences.

Cheers!

What about Golden Helix Genome Browser?