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  • Differentially Methylated Regions

    Dear all,

    I am wondering if someone knows if there is any validation dataset (cell types, human or mouse ..etc, normal or patients) which contains validated differentially methylated regions DMR (or CpG positions).
    I need this data in order to use it to test some differentially methylated CpGs (regions) if they are correct or not.

  • #2
    There's the annotation data from the Illumina human methylation chip, which should contain probes that have been tested and found to be differentially methylated in the human population.

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    • #3
      Thanks very much @gringer for your reply.
      Is this annotation data available for public download? if yes, can you please post a link to that resource.
      I tried to read about (Illumina human methylation chip) from http://www.illumina.com/products/met...chip_kits.ilmn
      While I found information about DMR, but did not find link to such data.

      Thanks in advance,

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      • #4
        Here are two links:

        * Illumina website -- from the page you linked to, go to product support page, then downloads, then product files

        * Bioconductor packages -- Illumina is there under 'I'
        Last edited by gringer; 10-29-2013, 12:26 PM.

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        • #5
          Thank you very much indeed @gringer. That was of great help !

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