Wig correlation

[Liy]

Hi all,

I've made several correlation with my ChIP-seq data (hg19) wig files (variable step) with ENCODE .bigWig files with wigCorrelate software. It makes the correlation, is this correalation valid?

Can you correlate wig with bigWig?
Which is the best way to create wig files?

Thank you for your answer.
L

[dawe]

You can use wigCorrelate for bedgraph, wig and bigwig files. It does pearson correlation on intervals that have non-zero value on both the datasets.

[Liy]

Thank you!