I am doing some analysis using XHMM. I was adviced to use a value of 12 as the mean number of targets. Being a recent convert to bioinformatics, I am a bit confused about what a target is? The output gives a variable called NUM_TARG. Is target in XHMM the same as markers in VarScan2? OR does a target correspond to 1 EXON? Does it have any relationship to the mean number of targets. I would really appreciate if some one who has used XHMM could enlighten me a bit.
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM