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I am doing some analysis using XHMM. I was adviced to use a value of 12 as the mean number of targets. Being a recent convert to bioinformatics, I am a bit confused about what a target is? The output gives a variable called NUM_TARG. Is target in XHMM the same as markers in VarScan2? OR does a target correspond to 1 EXON? Does it have any relationship to the mean number of targets. I would really appreciate if some one who has used XHMM could enlighten me a bit.
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM -
Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...03-22-2024, 06:39 AM