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Hi,
I have a problem that I can't find a solution anywhere.
In hawkeye (assembly visualisation sofware of Amos), we can see a graphic of "coverage stat" that correspond to the A-statistic calculation. I want to calculate this statistic in all points of the contig like in this softwtare.
I finded a PDF in internet that explaine how to calculate it:
A-statistic : Model the "arrival" of reads along the length of a unitig as a Poisson process:
G: length of genome
N: total number of reads
k: number of reads in the unitig
D : the distance between the start of the rst read to the start of the
kth read
A-statistic = DN/G log (e) - k log (2)
Anyway, I can't applicate it in differents points of contig so that I can have a graphic.
Can you to give me some explination or example to calculate it?
Thank you very much
I have a problem that I can't find a solution anywhere.
In hawkeye (assembly visualisation sofware of Amos), we can see a graphic of "coverage stat" that correspond to the A-statistic calculation. I want to calculate this statistic in all points of the contig like in this softwtare.
I finded a PDF in internet that explaine how to calculate it:
A-statistic : Model the "arrival" of reads along the length of a unitig as a Poisson process:
G: length of genome
N: total number of reads
k: number of reads in the unitig
D : the distance between the start of the rst read to the start of the
kth read
A-statistic = DN/G log (e) - k log (2)
Anyway, I can't applicate it in differents points of contig so that I can have a graphic.
Can you to give me some explination or example to calculate it?
Thank you very much