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Dear fellows –
I have a task to overlay the “good and known” single-cell annotations on the newly generated PC matrix (or its corresponding knn-graph) of the same dataset (cells retain annotations). Cell types may differ in the new clustering, but also may largely overlap with the known labels.
Is there an automated way (or utility) to estimate cell label fitness in a clustering (with some confidence stats)?
Highly appreciating in advance,
Leo
I have a task to overlay the “good and known” single-cell annotations on the newly generated PC matrix (or its corresponding knn-graph) of the same dataset (cells retain annotations). Cell types may differ in the new clustering, but also may largely overlap with the known labels.
Is there an automated way (or utility) to estimate cell label fitness in a clustering (with some confidence stats)?
Highly appreciating in advance,
Leo