I've used SeqAnswers extensively in my PhD so now it's time to give something back!
I have created a new tool for population genetics which objectively analyzes ancestry profiles produced by the Bayesian population genetics software Structure, InStruct and BAPS. The traditional approach is to plot these ancestry profiles using distruct but the interpretation of these plots has then been subjective. ObStruct uses the R2 statistic to objectively test the membership of individuals to specified populations and determine which sampled and inferred populations contribute most to the overall structure in the data. It also tests significance by employing a permutation approach.
The publication for ObStruct is available as of today for free over at PLoS ONE on their website as well as in PDF form.
You can download ObStruct and a manual from our lab website here.
If you have any questions about ObStruct or issues with using it, please let me know and I'd be happy to help!
I have created a new tool for population genetics which objectively analyzes ancestry profiles produced by the Bayesian population genetics software Structure, InStruct and BAPS. The traditional approach is to plot these ancestry profiles using distruct but the interpretation of these plots has then been subjective. ObStruct uses the R2 statistic to objectively test the membership of individuals to specified populations and determine which sampled and inferred populations contribute most to the overall structure in the data. It also tests significance by employing a permutation approach.
The publication for ObStruct is available as of today for free over at PLoS ONE on their website as well as in PDF form.
You can download ObStruct and a manual from our lab website here.
If you have any questions about ObStruct or issues with using it, please let me know and I'd be happy to help!