Hi all,
I try to further accelerate Bowtie2 alignment by separating input file to several pieces and using Hadoop-like computing framework to execute.
Based on my understanding, Bowtie2 aligns each pair of read independently.
However, when I separate input files into two parts and merge two outputs of Bowtie2, the content of result file is somewhat not consistent with that of result file generated without separating input.
I would like to ask whether Bowtie2 has some dependent task inside?
Does separating files and then merging the output make sense in Bowtie2?
Thanks.
I try to further accelerate Bowtie2 alignment by separating input file to several pieces and using Hadoop-like computing framework to execute.
Based on my understanding, Bowtie2 aligns each pair of read independently.
However, when I separate input files into two parts and merge two outputs of Bowtie2, the content of result file is somewhat not consistent with that of result file generated without separating input.
I would like to ask whether Bowtie2 has some dependent task inside?
Does separating files and then merging the output make sense in Bowtie2?
Thanks.
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