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  • AdrianP
    Senior Member
    • Apr 2011
    • 130

    #1

    How to phase haplotypes in a highly polymorphic genome from NGS data

    Hello,

    I have a highly polymorphic (10% polymorphism rate) genome. I expect this variation to be due to heterozygosity. What is the best way to try and phase my haplotypes?

    I found samtools has such a module called phase, and I phased my .bam file. However, I have no idea what to do with it to analyze the ouput. I wanted to be able to extract the build phased haplotypes and to measure their frequencies.

    Thank you.

    Replica: http://www.biostars.org/p/91604/
    Last edited by AdrianP; 01-24-2014, 12:43 PM.
  • sunyuhui
    Junior Member
    • Aug 2010
    • 3

    #2
    I'm also facing the same problem. Any suggestions?

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