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  • diya
    Member
    • Nov 2010
    • 11

    #1

    statistical test for a geneset between two groups

    hi,

    is there any statistical test that can test for significant of a geneset between two groups ?
  • dpryan
    Devon Ryan
    • Jul 2011
    • 3478

    #2
    For the normal methods (e.g., David, GOrilla, or any other program using a hypergeometric test), one would first call differentially expressed genes and then use that to determine enrichment. You might instead look into the camera() and roast() functions in limma or GSEA from the Broad Institute.

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