Seqanswers Leaderboard Ad

Collapse
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • chayan
    replied
    Originally posted by southan View Post
    You can use the Mclust package.

    (http://www.stat.washington.edu/mclust/)

    Change the parameter modelNames to obtain a suitable model (e.g., EII).
    thanks.. but i have never used R also... what i understand from the Mclust manual, if my matrix is like this

    A B C D E
    i 20 30 15 43 87
    ii 12 54 3 76 56
    iii 45 78 4 99 54

    i should use the modelName "VII"/"VVV" or other unequal volume or varying volume from the multivariate mixture??

    another thing, how to prepare the input file from the excel to feed into mclust??

    thanks a lot

    Leave a comment:


  • chayan
    replied
    thanks to both of you. As i am going through both the manuals, it will take some time as i am a hardcore biology guy, i want to clear one my query.. my matrix structure is like this
    A B C D E
    i 20 30 15 43 87
    ii 12 54 3 76 56
    iii 45 78 4 99 54

    now i want to cluster this based on the A, B, C, D, E based on the values of i, ii and iii...can i use "beta_diversity.py" from the qiime package..? then dont know basically how to generate to file format required for this as the prior steps are not same...


    thanks

    Leave a comment:


  • southan
    replied
    You can use the Mclust package.

    (http://www.stat.washington.edu/mclust/)

    Change the parameter modelNames to obtain a suitable model (e.g., EII).

    Leave a comment:


  • GenoMax
    replied
    Try MEGA: http://megasoftware.net/

    You should read the manual first to see if this would be appropriate to do with the dataset you have.

    Leave a comment:


  • chayan
    started a topic Clustering a two-D matrix

    Clustering a two-D matrix

    Hii All,

    I have generated a 2-D matrix based on NGS data which has cog scores in one axis (Y-axis) and sample no in other axis. Now i want to cluster this matrix based on the cog scores to find similarity between different sampling points and finally construct a UPGMA tree based on the output. Can any one suggest me a simple way to do this?? I don't have much knowledge about this...

    Thanks for any help in advance...

    Regards

    Chayan

Latest Articles

Collapse

  • seqadmin
    Pathogen Surveillance with Advanced Genomic Tools
    by seqadmin




    The COVID-19 pandemic highlighted the need for proactive pathogen surveillance systems. As ongoing threats like avian influenza and newly emerging infections continue to pose risks, researchers are working to improve how quickly and accurately pathogens can be identified and tracked. In a recent SEQanswers webinar, two experts discussed how next-generation sequencing (NGS) and machine learning are shaping efforts to monitor viral variation and trace the origins of infectious...
    03-24-2025, 11:48 AM
  • seqadmin
    New Genomics Tools and Methods Shared at AGBT 2025
    by seqadmin


    This year’s Advances in Genome Biology and Technology (AGBT) General Meeting commemorated the 25th anniversary of the event at its original venue on Marco Island, Florida. While this year’s event didn’t include high-profile musical performances, the industry announcements and cutting-edge research still drew the attention of leading scientists.

    The Headliner
    The biggest announcement was Roche stepping back into the sequencing platform market. In the years since...
    03-03-2025, 01:39 PM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by seqadmin, 03-20-2025, 05:03 AM
0 responses
41 views
0 reactions
Last Post seqadmin  
Started by seqadmin, 03-19-2025, 07:27 AM
0 responses
49 views
0 reactions
Last Post seqadmin  
Started by seqadmin, 03-18-2025, 12:50 PM
0 responses
36 views
0 reactions
Last Post seqadmin  
Started by seqadmin, 03-03-2025, 01:15 PM
0 responses
192 views
0 reactions
Last Post seqadmin  
Working...