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  • nilshomer
    Nils Homer
    • Nov 2008
    • 1283

    #1

    Samtools pileup indel ploidy

    Is there a convention to distinguish between heterozygous indels and homozygous indels in samtools' pileup? I have been running under the assumption that they look like I describe below, but looking at the indel frequency conditioned on the call on some simulated data there seems to be a fair number of heterozygotes that should have been called homozygous. Maybe pileup does not distinguish between het/hom in indels?

    HET
    Code:
    chr22    49513623    *    */-G    352    352    45    30    *    -G    18    12    0    0    0
    HET
    Code:
    chr22    49515653    *    -G/*    121    721    49    27    -G    *    20    7    0    0    0
    HOM
    Code:
    chr22    49531477    *    +G/+G    42    919    45    28    +G    *    23    5    0    0    0
    UNKNOWN (Multiple alleles)
    Code:
    chr22    34169351    *    +CC/+C    6    290    42    12    +CC    +C    8    1    3    3    0
  • bardou
    Junior Member
    • Jun 2010
    • 2

    #2
    Hi all,

    I'm also interesting by this one...
    Nobody can help ?

    Thanks

    Comment

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