Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • polarfire
    Junior Member
    • Aug 2014
    • 2

    #1

    Script to count parsimony informative sites

    I have hundreds of alignments, and I am curious if there is a script or tool out there that can simply count the number of parsimony informative sites in any given alignment?

    I know you can get this information by loading it into a phylogenetics program (e.g. PAUP or MrBayes), but if anyone knows of a script that can do this so it can be automated and done quickly I'd appreciate it!
  • themerlin
    Member
    • Feb 2010
    • 51

    #2
    No promises that it works correctly, but here's something that I had sitting around:

    count and extract parsimony informative SNPs from a multi-fasta - extract_PI_SNPs.py


    You need BioPython to run and it assumes no gaps. In addition to reporting the number of PI SNPs, it also prints a new multi-fasta with only those sites included. Feel free to edit it as you see fit.

    J

    Comment

    • polarfire
      Junior Member
      • Aug 2014
      • 2

      #3
      Thanks

      Thanks for that script!

      I also found out you can do it with the function pis() in the R library phyloch. That function also allows for gaps.

      Comment

      Latest Articles

      Collapse

      • SEQadmin2
        Multiomic Liquid Biopsy: What DNA/RNA Panels Reveal That DNA Alone Can’t
        by SEQadmin2



        Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?

        Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating
        ...
        10-14-2026, 09:55 AM
      • SEQadmin2
        New Genomics Technologies Take Aim at Long-Standing Limits
        by SEQadmin2


        Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.

        We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing
        ...
        09-28-2026, 10:25 AM

      ad_right_rmr

      Collapse

      News

      Collapse

      Topics Statistics Last Post
      Started by SEQadmin2, Today, 11:13 AM
      0 responses
      10 views
      0 reactions
      Last Post SEQadmin2  
      Started by SEQadmin2, Today, 10:48 AM
      0 responses
      9 views
      0 reactions
      Last Post SEQadmin2  
      Started by SEQadmin2, 10-15-2026, 10:52 AM
      0 responses
      32 views
      0 reactions
      Last Post SEQadmin2  
      Started by SEQadmin2, 10-14-2026, 05:39 AM
      0 responses
      40 views
      0 reactions
      Last Post SEQadmin2  
      Working...