See here for primary course announcement and registration.
This course is designed for users who have experience with writing R scripts, and who now want to advance one step further, into producing more durable and robust software projects and code that is usable by others.
The first part of the course will introduce object-oriented programming using R's S3 and S4 system and describe how to define classes, generic functions and methods. It will also present how to create Bioconductor-compliant R packages and document them. The second part will focus on various advanced topics in R programming such as unit testing, debugging, profiling and calling C/C++ code. It will also describe how to write efficient and elegant code using vectorisation, parallelization, and the functional programming paradigm. Finally, creating web applications with shiny will be discussed.
These topics will be illustrated using a small real-life bioinformatic case study. Participants will produce, at the end of the course, a fully fledged Bioconductor compliant R package.
Pre-requisites: Good knowledge of R and active programming experience. Familiarity with object-oriented programming and LaTeX is helpful, but not essential.
The course will take place on Thursday and Friday 15-16. January 2015 at EMBL Heidelberg, Courtyard A+B room (travel information).
See here for primary course announcement and registration.
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...-
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Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing...-
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