Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • Niloofar
    Junior Member
    • May 2012
    • 9

    #1

    error in Genemark-ES

    I am trying to use Genemark-ES. The installation went well and the program starts working, however, I get an error message:

    Can't exec "/home/ubuntu/gmes/gmes/make_mat.v3.0.ini.csh": No such file or directory at /home/ubuntu/gmes/gmes/gm_es.pl line 270.
    Died at /home/ubuntu/gmes/gmes/gm_es.pl line 270.

    However, I can see that "make_mat.v3.0.ini.csh" is actually there. So I am confused why I am getting this error and how to resolve it.

    Can anyone help with this please?
  • GenoMax
    Senior Member
    • Feb 2008
    • 7142

    #2
    You probably have to add execute permissions for the script file. Try this.

    Code:
    $ chmod a+x /home/ubuntu/gmes/gmes/make_mat.v3.0.ini.csh
    If you are using a non-admin account then you may need to use "sudo".

    Comment

    • Niloofar
      Junior Member
      • May 2012
      • 9

      #3
      Dear GenoMax

      Thanks a lot for your quick reply.
      I did accordingly but I am still getting the same error

      Comment

      • GenoMax
        Senior Member
        • Feb 2008
        • 7142

        #4
        Does the file have code in it?

        Comment

        • SES
          Senior Member
          • Mar 2010
          • 275

          #5
          Originally posted by GenoMax View Post
          You probably have to add execute permissions for the script file. Try this.

          Code:
          $ chmod a+x /home/ubuntu/gmes/gmes/make_mat.v3.0.ini.csh
          If you are using a non-admin account then you may need to use "sudo".
          It's not a permissions issue or Perl would say:
          Code:
          Permission denied at /path/to/gm_es.pl line xx
          Or, since the whole script is really just a bunch of shell commands, executing a command with "system" from Perl would produce a similar error from the shell (depending on the default shell):
          Code:
          sh: make_mat.v3.0.ini.csh: Permission denied
          But those are not the errors we see, so there must me something funny with this distribution where the paths are incorrect. FWIW, I could never get this program working for different reasons, and looking at the code convinced me not to try.

          Comment

          • Niloofar
            Junior Member
            • May 2012
            • 9

            #6
            Originally posted by GenoMax View Post
            Does the file have code in it?
            Sorry GenoMax, I cannot understand the question. As you may have alrady noticed, I am quite new to Linux. Would you please explain which file you mean?

            Comment

            • Niloofar
              Junior Member
              • May 2012
              • 9

              #7
              Originally posted by SES View Post
              It's not a permissions issue or Perl would say:
              Code:
              Permission denied at /path/to/gm_es.pl line xx
              Or, since the whole script is really just a bunch of shell commands, executing a command with "system" from Perl would produce a similar error from the shell (depending on the default shell):
              Code:
              sh: make_mat.v3.0.ini.csh: Permission denied
              But those are not the errors we see, so there must me something funny with this distribution where the paths are incorrect. FWIW, I could never get this program working for different reasons, and looking at the code convinced me not to try.
              Thanks, SES
              Yes, I can see on the web that many users have had problems with GeneMark. Thanks for your reply

              Comment

              Latest Articles

              Collapse

              • SEQadmin2
                Beyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool
                by SEQadmin2



                CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).

                Despite this, “CRISPR helped turn genome editing from a specialized technique into
                ...
                07-31-2026, 11:01 AM
              • SEQadmin2
                Proteomic Platforms: How to Choose the Right Analytical Strategy to Improve Detection and Clinical Applications
                by SEQadmin2


                Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.

                The systematic characterization of the human proteome has
                ...
                07-20-2026, 11:48 AM

              ad_right_rmr

              Collapse

              News

              Collapse

              Topics Statistics Last Post
              Started by SEQadmin2, 08-06-2026, 07:41 AM
              0 responses
              16 views
              0 reactions
              Last Post SEQadmin2  
              Started by SEQadmin2, 08-03-2026, 10:13 AM
              0 responses
              31 views
              0 reactions
              Last Post SEQadmin2  
              Started by SEQadmin2, 07-31-2026, 02:55 AM
              0 responses
              42 views
              0 reactions
              Last Post SEQadmin2  
              Started by SEQadmin2, 07-24-2026, 12:17 PM
              0 responses
              26 views
              0 reactions
              Last Post SEQadmin2  
              Working...