Tweet
Hi Guys,
I ran SVDetect on Next generation paired end data and got the output but I am confused as to how to interpret the intrachromosomal deletions.
My understanding of the basic deletion meaning is that a part of a chromosome is deleted. However SVDetect gives two coordinates for the deletion position which is confusing to me. Can anyone explain this for me please?
I will give the header and an example of a deletion below:
In this example SVDetect detected a deletion in chromosome 15 apparently at 8996748-8997144 but then it mentions that it was also in the same chromosome at 8997145-8997470.
Header:
chr_type SV_type BAL_type chromosome1 start1-end1 average_dist chromosome2 start2-end2 nb_pairs score_strand_filtering score_order_filtering score_insert_size_filtering final_score breakpoint1_start1-end1 breakpoint2_start2-end2
Deletion:
INTRA DELETION UNBAL chr15 8996748-8997144 416 chr15 8997145-8997470 19 100% 100% 100% 1 8997144-8997130 8997089-8997146
I would greatly appreciate your help as I am trying to wrap up this project now.
I ran SVDetect on Next generation paired end data and got the output but I am confused as to how to interpret the intrachromosomal deletions.
My understanding of the basic deletion meaning is that a part of a chromosome is deleted. However SVDetect gives two coordinates for the deletion position which is confusing to me. Can anyone explain this for me please?
I will give the header and an example of a deletion below:
In this example SVDetect detected a deletion in chromosome 15 apparently at 8996748-8997144 but then it mentions that it was also in the same chromosome at 8997145-8997470.
Header:
chr_type SV_type BAL_type chromosome1 start1-end1 average_dist chromosome2 start2-end2 nb_pairs score_strand_filtering score_order_filtering score_insert_size_filtering final_score breakpoint1_start1-end1 breakpoint2_start2-end2
Deletion:
INTRA DELETION UNBAL chr15 8996748-8997144 416 chr15 8997145-8997470 19 100% 100% 100% 1 8997144-8997130 8997089-8997146
I would greatly appreciate your help as I am trying to wrap up this project now.